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Published 
10/24/2009
Title: Immunology Team-Based Learning: Receptor Diversity & Antigen Presentation

Resource Type: Other

Primary Author: Wayne McCormack, PhD

Institution: University of Florida College of Medicine
Description: This resource includes a pool of readiness assurance questions and group assignment activities that may be used in different combinations to create team-based learning (TBL) exercises to help learners understand the following immunological principles and how to apply them in experimental settings: the molecular mechanisms by which diverse antigen receptors are created in developing B and T lymphocytes, differences between immunoglobulin and T cell receptor (TCR) structure and function, the geno ....
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Published 
10/22/2009
Title: Thalassaemia PBL Case

Resource Type: PBL Materials

Primary Author: Niels Larsen, Assoc. Professor

Institution: Ross University
Description: This resource is a problem based learning case (PBL) on alpha-thalassaemia syndrome (patient with HbH disease). The case has been used in a PBL format where the first 5-pages of the case are handed out in session one, 3 more pages are handed out after hearing and discussing the research in session two, and finally the postscript and the expected learning issues are handed out during session three. The case naturally leads the students to study causes of fatigue and then anemia, especially microc ....
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Published 
09/22/2009
Title: Sickle Cell Trait and Sickle Cell Disease: A Case Study

Resource Type: Exercise

Primary Author: Shoumita Dasgupta, PhD

Institution: Boston University School of Medicine
Description: This case is a classical example of an African American individual who is a heterozygous for sickle cell disease and who does not manifest any symptoms until he encounters extreme physical conditions. This case explores: The initial presentation of sickle cell symptoms in a heterozygote: The assembly of a pedigree and calculation of genetic risk for transmission of the mutation: The biochemical and genetic testing options that are available for diagnostic and pre-conception genetic testing in si ....
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Published 
09/08/2009
Title: PBL Case on Child Abuse/Hemophilia A

Resource Type: PBL Materials

Primary Author: Niels Larsen, Assoc. Professor

Institution: Ross University
Description: This resource is a problem based learning (PBL) case on the dichotomy of child abuse and hemophilia A. The case has been used in a (PBL) format where the first 4 pages of the case are handed out in session one, 6 more pages are handed out after hearing and discussing the research in session two, and finally the postscript and the expected learning issues are handed out during session three. At the end of session one, the case will have lead the students to research issues related to child abuse ....
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Published 
07/29/2009
Title: Rachel Jacobson's Painful Hip

Resource Type: PBL Materials

Primary Author: Marshall Anderson, PhD

Institution: Indiana University School of Medicine
Description: This is a PBL case for a medical biochemistry/molecular biology course suitable for first or second year medical students; with the incorporation of images it would be suitable for a histology course or an integrated biochem-histology-cell biology course. The case is a young girl who is diagnosed as a compound heterozygote for Gaucher Disease and it treated with enzyme replacement therapy.
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